The suggested mode of action concept is based on (i) the mode of action of the pharmaceutical taking the available toxicological information into account, (ii) the degree of sequence homology between the human drug target and the potential target in aquatic organisms and (iii) the importance of pathways affected by the pharmaceutical.
(ii) the degree of sequence homology between the human drug target and the potential target in aquatic organisms
(ii) 人用医薬品の標的(部位)と水生生物の潜在的な標的(部位)との間の配列相同性の度合い
No comments:
Post a Comment